Evaluación del efecto de fibroblastos MRC-5 en condiciones de inflamación sobre la respuesta de células de cáncer de ovario expuestas a nanopartículas Dox/MgO
dc.audience | Especializada | |
dc.contributor.advisor | Wiesner Reyes, Magdalena | |
dc.contributor.advisor | Gutierrez, Luz Dary | |
dc.contributor.author | Buitrago Sanabria, Mariana | |
dc.date.accessioned | 2024-10-07T22:15:49Z | |
dc.date.available | 2024-10-07T22:15:49Z | |
dc.date.created | 0024-05-27 | |
dc.date.issued | 2024-10-07 | |
dc.description | Propia | |
dc.description.abstract | Ovarian cancer is one of the most common gynecological cancers and with the highest mortality in women. Cross-talk between cancer-associated fibroblasts and tumor cells has been correlated with chemoresistance, invasion, and metastasis. In this study, the effect of prestimulated fibroblasts on ovarian cancer tumor cells exposed to Dox/MgO was evaluated by invasion, scratch wound and MTT assays. | |
dc.description.degreelevel | Pregrado | |
dc.description.degreename | Bioquímico(a) | |
dc.description.degreetype | Investigación | |
dc.description.notes | Presencial | |
dc.description.sponsorship | UAN Proyectos de ciencia, tecnología, innovación y creación artística | |
dc.description.tableofcontents | El cáncer de ovario es uno de los cánceres ginecológicos más frecuentes y de mayor mortalidad en mujeres. La comunicación cruzada entre los fibroblastos asociados al cáncer y las células tumorales se ha correlacionado con quimioresistencia, invasión y metástasis. En este estudio se evaluó el efecto de fibroblastos preestímulados sobre células tumorales de cáncer de ovario expuestas a Dox/MgO, mediante ensayo de invasión, de herida por raspado y MTT. | |
dc.description.version | final | |
dc.format.medium | ||
dc.identifier.uri | https://repositorio.uan.edu.co/handle/123456789/10299 | |
dc.language.iso | Español | |
dc.publisher | Universidad Antonio Nariño | |
dc.publisher.campus | Bogotá - Circunvalar | |
dc.publisher.faculty | Facultad de Ciencias | |
dc.publisher.program | Bioquímica | |
dc.rights | Acceso a solo metadatos | |
dc.rights.accessrights | info:eu-repo/semantics/closedAccess | spa |
dc.rights.coar | http://purl.org/coar/access_right/c_16ec | spa |
dc.rights.license | Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) | spa |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/ | spa |
dc.source | reponame:Repositorio Institucional UAN | |
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dc.source.bibliographicCitation | Berek, J. S., Renz, M., Kehoe, S., Kumar, L., & Friedlander, M. (2021). Cancer of the ovary, fallopian tube, and peritoneum: 2021 update. International Journal of Gynecology and Obstetrics, 155(S1), 61–85. https://doi.org/10.1002/ijgo.13878 | |
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dc.source.bibliographicCitation | Dai, J. min, Sun, K., Li, C., Cheng, M., Guan, J. hua, Yang, L. na, & Zhang, L. wen. (2023). Cancer- associated fibroblasts contribute to cancer metastasis and apoptosis resistance in human ovarian cancer via paracrine SDF-1α. Clinical and Translational Oncology, 25(6), 1606–1616. https://doi.org/10.1007/s12094-022-03054-9 | |
dc.source.bibliographicCitation | de Souza, J. C., Ribeiro, R. S., Pimenta, T. M., da Silva Martins, B., & Rangel, L. B. A. (2023). The role of pro-inflammatory components, carcinoma-associated fibroblasts, and tumorassociated macrophages in ovarian cancer progression and metastasis. In Journal of Cancer Metastasis and Treatment (Vol. 9). OAE Publishing Inc. https://doi.org/10.20517/2394-4722.2022.91 | |
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dc.subject | Cáncer de ovario | |
dc.subject | Fibroblastos | |
dc.subject | Doxorrubicina | |
dc.subject | Nanopartículas | |
dc.subject | MgO | |
dc.subject.keyword | Ovarian cancer | |
dc.subject.keyword | Fibroblasts | |
dc.subject.keyword | Doxorubicin | |
dc.subject.keyword | Nanoparticles | |
dc.subject.keyword | MgO | |
dc.title | Evaluación del efecto de fibroblastos MRC-5 en condiciones de inflamación sobre la respuesta de células de cáncer de ovario expuestas a nanopartículas Dox/MgO | |
dc.type.coar | http://purl.org/coar/resource_type/c_7a1f | spa |
dc.type.coarversion | http://purl.org/coar/version/c_b1a7d7d4d402bcce | |
dc.type.document | Estudio descriptivo | |
dc.type.local | Tesis/Trabajo de grado - Monografía - Pregrado | spa |
dc.type.redcol | http://purl.org/redcol/resource_type/PIC | |
dc.type.version | Versión original del autor, Borrador, Manuscrito |
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