Cambios en las proteínas asociadas a estrés oxidativo de Apis mellifera expuestas al insecticida sistémico Imidacloprid.

dc.contributor.advisorArenas Suarez, Nelson Enriquespa
dc.contributor.authorGalindo Morales, Fredy Gonzalospa
dc.creator.cedula11821822296spa
dc.date.accessioned2023-07-31T20:22:03Z
dc.date.available2023-07-31T20:22:03Z
dc.date.issued2023-05-24spa
dc.description.abstractThe increase in agricultural crops has brought with it the increase in the use of insecticides, however, its application has collaterally impacted pollinating insects. Insecticides induce oxidative stress in bees, but the reason why it occurs has not yet been fully elucidated, which is why this study sought to describe the interactions between the insecticide imidacloprid with catalase, glutathione peroxidase and superoxide dismutase using molecular docking, as well as evaluating the expression changes of proteins related to oxidative stress of protein extracts from A. mellifera.eng
dc.description.abstractEl incremento de los cultivos agrícolas ha traído consigo el aumento del uso de insecticidas, sin embargo, su aplicación ha impactado colateralmente a insectos polinizadores. Los insecticidas inducen estrés oxidativo en abejas, mas, la razón por la cual se presenta, aún no se dilucida completamente, es por ello, que en este estudio se buscó describir las interacciones entre el insecticida imidacloprid con catalasa, glutatión peroxidasa y superóxido dismutasa mediante acoplamiento molecular, así como evaluar los cambios de expresión de las proteínas relacionadas con estrés oxidativo de extractos proteicos de A. mellifera.spa
dc.description.degreelevelPregradospa
dc.description.degreenameBioquímico(a)spa
dc.description.degreetypeInvestigaciónspa
dc.description.notesPresencialspa
dc.identifier.bibliographicCitationAguiar, J. M. R. B. V., Nocelli, R. C. F., Giurfa, M., & Nascimento, F. S. (2023). Neonicotinoid effects on tropical bees: Imidacloprid impairs innate appetitive responsiveness, learning and memory in the stingless bee Melipona quadrifasciata. Science of The Total Environment, 877,162859. https://doi.org/10.1016/J.SCITOTENV.2023.162859spa
dc.identifier.bibliographicCitationAslam, B., Basit, M., Nisar, M. A., Khurshid, M., & Rasool, M. H. (2017). Proteomics: Technologies and Their Applications. Journal of Chromatographic Science, 55(2), 182–196. https://doi.org/10.1093/CHROMSCI/BMW167spa
dc.identifier.bibliographicCitationBalieira, K. V. B., Mazzo, M., Bizerra, P. F. V., Guimarães, A. R. de J. S., Nicodemo, D., & Mingatto, F. E. (2018). Imidacloprid-induced oxidative stress in honey bees and the antioxidant action of caffeine. Apidologie, 49(5), 562–572. https://doi.org/10.1007/S13592-018-0583-1/TABLES/3spa
dc.identifier.bibliographicCitationBlum, M., Chang, H. Y., Chuguransky, S., Grego, T., Kandasaamy, S., Mitchell, A., Nuka, G., Paysan-Lafosse, T., Qureshi, M., Raj, S., Richardson, L., Salazar, G. A., Williams, L., Bork, P., Bridge, A., Gough, J., Haft, D. H., Letunic, I., Marchler-Bauer, A., … Finn, R. D. (2021). The InterPro protein families and domains database: 20 years on. Nucleic Acids Research, 49(D1), D344–D354. https://doi.org/10.1093/NAR/GKAA977spa
dc.identifier.bibliographicCitationBoily, M., Sarrasin, B., DeBlois, C., Aras, P., & Chagnon, M. (2013). Acetylcholinesterase in honey bees (Apis mellifera) exposed to neonicotinoids, atrazine and glyphosate: laboratory and field experiments. Environmental Science and Pollution Research International, 20(8), 5603–5614.https://doi.org/10.1007/S11356-013-1568-2spa
dc.identifier.bibliographicCitationBrandt, A., Gorenflo, A., Siede, R., Meixner, M., & Büchler, R. (2016). The neonicotinoids thiacloprid, imidacloprid, and clothianidin affect the immunocompetence of honey bees (Apis mellifera L.). Journal of Insect Physiology, 86, 40–47. https://doi.org/10.1016/J.JINSPHYS.2016.01.001spa
dc.identifier.bibliographicCitationBuszewski, B., Bukowska, M., Ligor, M., & Staneczko-Baranowska, I. (2019). A holistic study of neonicotinoids neuroactive insecticides—properties, applications, occurrence, and analysis. Environmental Science and Pollution Research, 26(34), 34723–34740. https://doi.org/10.1007/S11356-019-06114-W/TABLES/3spa
dc.identifier.bibliographicCitationCasida, J. E., & Durkin, K. A. (2013). Neuroactive insecticides: Targets, selectivity, resistance, and secondary effects. Annual Review of Entomology, 58, 99–117. https://doi.org/10.1146/annurevento-120811-153645spa
dc.identifier.bibliographicCitationCastellano, I., Cecere, F., De Vendittis, A., Cotugno, R., Chambery, A., Di Maro, A., Michniewicz, A., Parlato, G., Masullo, M., Avvedimento, E. V., De Vendittis, E., & Ruocco, M. R. (2009). Rat mitochondrial manganese superoxide dismutase: Amino acid positions involved in covalent modifications, activity, and heat stability. Biopolymers, 91(12), 1215–1226. https://doi.org/10.1002/BIP.21208spa
dc.identifier.bibliographicCitationCatae, A. F., Roat, T. C., Pratavieira, M., Silva Menegasso, A. R. da, Palma, M. S., & Malaspina, O. (2017). Exposure to a sublethal concentration of imidacloprid and the side effects on target and nontarget organs of Apis mellifera (Hymenoptera, Apidae). Ecotoxicology 2017 27:2, 27(2), 109–121. https://doi.org/10.1007/S10646-017-1874-4spa
dc.identifier.instnameinstname:Universidad Antonio Nariñospa
dc.identifier.reponamereponame:Repositorio Institucional UANspa
dc.identifier.repourlrepourl:https://repositorio.uan.edu.co/spa
dc.identifier.urihttp://repositorio.uan.edu.co/handle/123456789/8343
dc.language.isospaspa
dc.publisherUniversidad Antonio Nariñospa
dc.publisher.campusBogotá - Circunvalarspa
dc.publisher.facultyFacultad de Cienciasspa
dc.publisher.programBioquímicaspa
dc.rightsAcceso abierto
dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.rights.coarhttp://purl.org/coar/access_right/c_abf2spa
dc.rights.licenseAttribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)spa
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/spa
dc.subjectAbeja, imidacloprid, pesticidas, proteómica, acoplamiento molecular.es_ES
dc.subjectimidacloprides_ES
dc.subjectpesticidases_ES
dc.subjectproteómicaes_ES
dc.subjectacoplamiento moleculares_ES
dc.subject.ddc574es_ES
dc.subject.ddc38.23 G158ces_ES
dc.subject.keywordBeees_ES
dc.subject.keywordimidacloprides_ES
dc.subject.keywordproteomicses_ES
dc.subject.keywordmolecular dockinges_ES
dc.subject.keywordpesticideses_ES
dc.titleCambios en las proteínas asociadas a estrés oxidativo de Apis mellifera expuestas al insecticida sistémico Imidacloprid.es_ES
dc.typeTrabajo de grado (Pregrado y/o Especialización)spa
dc.type.coarhttp://purl.org/coar/resource_type/c_7a1fspa
dc.type.coarversionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.versioninfo:eu-repo/semantics/acceptedVersionspa
dcterms.audienceGeneralspa
Files
Original bundle
Now showing 1 - 4 of 4
thumbnail.default.alt
Name:
2023_FredyGonzaloGalindoMorales.pdf
Size:
1.43 MB
Format:
Adobe Portable Document Format
Description:
thumbnail.default.alt
Name:
2023_FredyGonzaloGalindoMorales_Acta .pdf
Size:
1.51 MB
Format:
Adobe Portable Document Format
Description:
thumbnail.default.alt
Name:
2023_FredyGonzaloGalindoMorales_Autorización.pdf
Size:
323.12 KB
Format:
Adobe Portable Document Format
Description:
thumbnail.default.alt
Name:
2023_FredyGonzaloGalindoMorales_Autorización.pdf
Size:
323.12 KB
Format:
Adobe Portable Document Format
Description:
Collections