Efecto antimicrobiano in vitro del aceite esencial eucalyptus globulus labill sobre fusobacterium nucleatum, porphyromonas gingivalis y aggregatibacter actinomycetemcomitans. Revisión de la literatura

dc.contributor.advisorVásquez Quijano, Adiel Albertospa
dc.contributor.advisorSuárez Gélvez, Blanca Lynnespa
dc.contributor.authorGutiérrez Pineda, Sasha Valentinaspa
dc.contributor.authorUreña Cáceres, Emily Danielaspa
dc.creator.cedula1090522036spa
dc.creator.cedula1090528839spa
dc.date.accessioned2021-03-09T21:37:26Z
dc.date.available2021-03-09T21:37:26Z
dc.date.issued2020-11-23spa
dc.descriptionPropiaes_ES
dc.description.abstractThe use of herbal medicine in dentistry has shown good results in the treatment of periodontal diseases, especially Eucalyptus essential oil, apart from being a good source of antimicrobials, especially against Gram negative bacteria, it has shown to have a good anti-inflammatory effect. Objective. To determine, based on a literature review, the in vitro antimicrobial effect of Eucalyptus globulus labill essential oil on Fusobacterium nucleatum, Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans. Materials and methods. A compilation of articles was made using different biomedical platforms such as Pubmed, Science Direct, Academic Google, SciELO and Latindex, in this search the publications related to the antimicrobial effect of the essential oil of Eucalyptus globulus labill on periodontopathogens were identified, obtaining in total 48 articles with publication dates between 2000-2020, full text and written in English, Portuguese and Spanish. Results. The information from different minimum inhibitory concentrations (MIC) of the essential oil of Eucalyptus globulus Labill were compiled. According to what was reported by the different authors, for P. gingivalis a MIC of 0.28mg/ml is necessary; F. nucleatum is 1.14mg/ml and A. actinomycetemcomitans is 9.13mg/ml. Conclusion. It was determined, through literature review, that Eucalyptus globulus Labill essential oil has an antimicrobial effect on Fusobacterium nucleatum, Porphyromonas gingivalisand Aggregatibacter actinomycetemcomitans, where it was evidenced that a longer exposure time to the essential oil is necessary in the latter. Keywords. Fusobacterium nucleatum, Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans, herbal medicine, essential oil, Eucalyptus.eng
dc.description.abstractEl uso de la fitoterapia en odontología ha mostrado buenos resultados en el tratamiento de las enfermedades periodontales en especial el aceite esencial de Eucalipto, aparte de ser una buena fuente de antimicrobianos, especialmente contra bacterias Gram negativas, ha mostrado tener un buen efecto como antiinflamatorio. Objetivo. Determinar con base en una revisión de literatura, el efecto antimicrobiano in vitro del aceite esencial de Eucalyptus globulus labill sobre Fusobacterium nucleatum, Porphyromonas gingivalis y Aggregatibacter actinomycetemcomitans. Materiales y Métodos. Se realizó una recopilación de artículos en donde se utilizaron diferentes plataformas biomédicas como Pubmed, Science Direct, Google académico, SciELO y Latindex, en dicha búsqueda se identificaron las publicaciones relacionadas al efecto antimicrobiano del aceite esencial de Eucalyptus globulus labill sobre periodontopatógenos, obteniendo en total 48 artículos con fechas de publicación entre los años 2000-2020, texto completo y escritos en idioma inglés, portugués y español. Resultados. Se recopiló información de las distintas concentraciones mínimas inhibitorias (CMI) del aceite esencial de Eucalyptus globulus Labill que según lo reportado por los diferentes autores, para P. gingivalis es necesaria una CMI de 0.28mg/ml; F. nucleatum es de 1.14mg/ml y A. actinomycetemcomitans es de 9,13mg/ml. Conclusión. Se determinó, mediante revisión de la literatura, que el aceite esencial de Eucalyptus globulus Labill posee efecto antimicrobiano sobre Fusobacterium nucleatum, Porphyromonas gingivalis y Aggregatibacter actinomycetemcomitans en donde se evidencio que en este último es necesario un mayor tiempo de exposición al aceite esencial. Palabras claves. Fusobacterium nucleatum, Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans, herbal medicine, essential oil, Eucalyptus.spa
dc.description.degreelevelPregradospa
dc.description.degreenameOdontólogo(a)spa
dc.description.notesPresencialspa
dc.identifier.bibliographicCitationÅberg, C. H., Kelk, P., & Johansson, A. (2015). Aggregatibacter actinomycetemcomitans: virulence of its leukotoxin and association with aggressive periodontitis. Virulence, 6(3), 188–195.spa
dc.identifier.bibliographicCitationAkkaoui, S., & Ennibi, O. K. (2017). Use of traditional plants in management of halitosis in a Moroccan population. Journal of Intercult Ethnopharmacology, 6(3), 267-273.spa
dc.identifier.bibliographicCitationAkkaoui, S., Johansson, A., Yagoubi, M., Haubek, D., El Hamidi, A., Rida, S.,… Ennibi, O. (2020). Chemical Composition, Antimicrobial activity, in Vitro Cytotoxicity and Leukotoxin Neutralization of Essential Oil from Origanum vulgare against Aggregatibacter actinomycetemcomitans. Pathogens, 9(192), 1-14.spa
dc.identifier.bibliographicCitationAldoghaim, F.S., Flematti, G.R., & Hammer, K.A. (2018). Antimicrobial Activity of Several Cineole-RichWestern Australian Eucalyptus Essential Oils. Microorganisms, 6(4), 122-133.spa
dc.identifier.bibliographicCitationAlmeida, L. C., Andrade, C., & Teixeira, R. R. (2016). Chemical Variability and Biological Activities of Eucalyptus spp. Essential Oils. Molecules, 21(12), 1-33.spa
dc.identifier.bibliographicCitationBankur, P. K., Mathew, M., Almalki, S. A., Jalaluddin, M., Jayanti, I., & Durgaraju, M. (2019). An In Vitro Evaluation of Antibacterial Efficacy of Various Concentration of Eucalyptus globulus Leaf Extract on Periodontal Pathogens. The Journal of Contemporary Dental Practice, 20(9), 1041-1044.spa
dc.identifier.bibliographicCitationBao, K., Belibasakis, G. N., Thurnheer, T., Aduse-Opoku, J., Curtis, M. A., & Bostanci, N. (2014). Role of Porphyromonas gingivalis gingipains in multi-species biofilm formation. BMC microbiology, 14(258), 1-8.spa
dc.identifier.bibliographicCitationBelibasakis, G. N., Maula, T., Bao, K., Lindholm, M., Bostanci, N., Oscarsson, J.,…Johansson, A. (2019). Virulence and Pathogenicity Properties of Aggregatibacter actinomycetemcomitans. Pathogens (Basel, Switzerland), 8(4), 222-245.spa
dc.identifier.bibliographicCitationBonilla, D. M., Mendoza, Y., Moncada, C. E., Murcia, O., Rojas, A. P., Calle, J., Pinzon, R., y Nerio, L. (2016). Efecto del aceite esencial de Rosmarinus officinalis sobre Porphyromonas gingivalis cultivada in vitro. Revista colombiana de ciencias químico farmacéuticas, 45(2), 275-287.spa
dc.identifier.bibliographicCitationBostanci, N., & Belibasakis, G. (2012). Porphyromonas gingivalis: an invasive and evasive opportunistic oral pathogen. Federation of European Microbiological Societies Microbiol Lett, 333(2012), 1-9.spa
dc.identifier.bibliographicCitationBrochot, A., Guilbot, A., Haddioui, L., & Roques, C. (2017). Antibacterial, antifungal, and antiviral effects of three essential oil blends. MicrobiologyOpen, 6(4), 1-6.spa
dc.identifier.bibliographicCitationCoppenhagen-Glazer, S., Sol, A., Abed, J., Naor, R., Zhang, X., Han, Y. W., & Bachrach, G. (2015). Fap2 of Fusobacterium nucleatum is a galactose-inhibitable adhesin involved in coaggregation, cell adhesion, and preterm birth. Infection and immunity, 83(3), 1104–1113.spa
dc.identifier.bibliographicCitationDamjanović-Vratnica1, B., Đakov, T., Šuković, D. &Damjanović, J. (2011). Antimicrobial Effect of Essential Oil Isolated from Eucalyptus globulus Labill from Montenegro. Czech Journal of Food Sciences, 29(3), 277-284.spa
dc.identifier.bibliographicCitationDíaz, J., Yáñez, J., Melgar, S., Álvarez, C., Rojas, C., y Vernal, R. (2012). Virulencia y variabilidad de Porphyromonas gingivalis y Aggregatibacter actinomycetemcomitans y su asociación a la periodontitis. Revista clínica de periodoncia, implantología y rehabilitación oral, 5(1), 40-45.spa
dc.identifier.bibliographicCitationDe Andrade, K. Q., Almeida-da-Silva, C., & Coutinho-Silva, R. (2019). Immunological Pathways Triggered by Porphyromonas gingivalis and Fusobacterium nucleatum: Therapeutic Possibilities?. Mediators of inflammation, 2019, 1-20.spa
dc.identifier.bibliographicCitationDe Godoi, S. N., Maciel, P., Rorato, M., Nascimento, K., Wagner, R., Klein, B.,…Ferreira, A. (2017). Evaluation of Stability and In Vitro Security of Nanoemulsions Containing Eucalyptus globulus Oil. BioMed Research International, 2017, 1-11.spa
dc.identifier.bibliographicCitationDe Oliveira, S. (2016). The effect of a homoeopathic and herbal Mouthwash formulation on the growth of Streptococcus salivarius and Fusobacterium nucleatum in vitro. (Tesis de PhD), Universidad de Johannesburg, Johannesburg, Sudáfrica.spa
dc.identifier.bibliographicCitationDe Oliveira, J. S., Pinto, M. E., Santana, L. A., Pinto, A. S., Di Lenardo, D., & Vasconcelos, D. F. (2016). Biological Effects of Medicinal Plants on Induced Periodontitis: A Systematic Review. International journal of dentistry, 2016(3719879), 1-10.spa
dc.identifier.bibliographicCitationElaissi, A., Rouis, Z., Mabrouk, S., Salah, K. B., Aouni, M., Khouja, M. L., Farhat, F.,…Harzallah-Skhiri, F. (2012). Correlation between chemical composition and antibacterial activity of essential oils from fifteen Eucalyptus species growing in the Korbous and Jbel Abderrahman arboreta (North East Tunisia). Molecules (Basel, Switzerland), 17(3), 3044–3057. Elaissi, A., Rouis, Z., Salem, N. A., Mabrouk, S., Ben Salem, Y., Salah, K. B.,…Khouja, M. L. (2012). Chemical composition of 8 eucalyptus species' essential oils and the evaluation of their antibacterial, antifungal and antiviral activities. BMC complementary and alternative medicine, 12(81), 1-15.spa
dc.identifier.bibliographicCitationEnersen, M., Nakano, K., & Amano, A. (2013) Porphyromonas gingivalis fimbriae. Journal of Oral Microbiology, 5(1), 1-10.spa
dc.identifier.bibliographicCitationErriu, M., Pili, F. M., Tuveri, E., Pigliacampo, D., Scano, A., Montaldo, C.,… Orrù, G. (2013). Oil Essential Mouthwashes Antibacterial Activity against Aggregatibacter actinomycetemcomitans: A Comparison between Antibiofilm and Antiplanktonic Effects. International journal of dentistry, 2013, 1-5.spa
dc.identifier.bibliographicCitationFardini, Y., Wang, X., Témoin, S., Nithianantham, S., Lee, D., Shoham, M., & Han, Y. W. (2011). Fusobacterium nucleatum adhesin FadA binds vascular endothelial cadherin and alters endothelial integrity. Molecular microbiology, 82(6), 1468–1480.spa
dc.identifier.bibliographicCitationGhaffar, A., Yameen, M., Kiran, S., Kamal, S., Jalal, F., Munir, B.,… Jabbar, A. (2015). Chemical Composition and in-Vitro Evaluation of the Antimicrobial and Antioxidant Activities of Essential Oils Extracted from Seven Eucalyptus Species. Molecules (Basel, Switzerland), 20(1), 20487–20498.spa
dc.identifier.bibliographicCitationGuerrero, B., Mojica, G., y Solano, K. (2018). Efecto antibacteriano del principio activo cinecol vs aceite esencial eucalipto sobre Porphyromonas gingivalis. (Tesis de pregrado). Universidad Antonio Nariño, Cúcuta, Colombia.spa
dc.identifier.bibliographicCitationGuven, Y., Ustun, N., Aksakal S. D., Topcuoglu, N., Aktoren, O., & Kulekci, G. (2018). Assessment of the endodontic microbiota of abscessed primary teeth using microarray technology. Indian Journal of Dental Research, 29(6), 781-786.spa
dc.identifier.bibliographicCitationHan, Y. W., Shi, W., Huang, G. T., Kinder Haake, S., Park, N. H., Kuramitsu, H., & Genco, R. J. (2000). Interactions between periodontal bacteria and human oral epithelial cells: Fusobacterium nucleatum adheres to and invades epithelial cells. Infection and immunity, 68(6), 3140–3146.spa
dc.identifier.bibliographicCitationHans, V. M., Grover, H. S., Deswal, H., & Agarwal, P. (2016). Antimicrobial Efficacy of Various Essential Oils at Varying Concentrations against Periopathogen Porphyromonas gingivalis. Journal of clinical and diagnostic research, 10(9), 16–19.spa
dc.identifier.bibliographicCitationHarkat-Madouri, L., Asma, B., Madani, K., Si Said, Z. B-O., Rigou, P., Grenier D., AllalouH.,…Boulekbache-Makhlouf, L. (2015). Chemical composition, antibacterial and antioxidant activities of essential oil of Eucalyptus globulus from Algeria. Industrial Crops and Products, 78(2015), 148–153.spa
dc.identifier.bibliographicCitationHerbert, B. A., Novince, C. M., & Kirkwood, K. L. (2016). Aggregatibacter actinomycetemcomitans, a potent immunoregulator of the periodontal host defense system and alveolar bone homeostasis. Molecular oral microbiology, 31(3), 207–227.spa
dc.identifier.bibliographicCitationHow, K. Y., Song, K. P., & Chan, K. G. (2016). Porphyromonas gingivalis: An Overview of Periodontopathic Pathogen below the Gum Line. Frontiers in microbiology, 7(53), 1-14.spa
dc.identifier.bibliographicCitationJohansson, A. (2011). Aggregatibacter actinomycetemcomitans leukotoxin: a powerful tool with capacity to cause imbalance in the host inflammatory response. Toxins, 3(3), 242–259.spa
dc.identifier.bibliographicCitationJuiz, P. J., Lucchese, A. M., Gambari, R., Piva, R., Penolazzi, L., Di Ciano, M., Trovatti, A. P.,…Avila-Campos, M. J. (2015). Essential oils and isolated compounds from Lippia alba leaves and flowers: Antimicrobial activity and osteoclast apoptosis. International journal of molecular medicine, 35(1), 211-217.spa
dc.identifier.bibliographicCitationKarbach, J., Ebenezer, S., Warnke, P. H., Behrens, E., & Al-Nawas, B. (2015). Antimicrobial effect of Australian antibacterial essential oils as alternative to common antiseptic solutions against clinically relevant oral pathogens. Clinical laboratory, 61(1-2), 61–68.spa
dc.identifier.bibliographicCitationKaur, M., & Kachlany, S. C. (2014). Aggregatibacter actinomycetemcomitans leukotoxin (LtxA; Leukothera) induces cofilin dephosphorylation and actin depolymerization during killing of malignant monocytes. Microbiology (Reading, England), 160(11), 2443–2452.spa
dc.identifier.bibliographicCitationLof, M., Janus, M. M., & Krom, B. P. (2017). Metabolic Interactions between Bacteria and Fungi in Commensal Oral Biofilms. Journal of fungi (Basel, Switzerland), 3(40), 1-13.spa
dc.identifier.bibliographicCitationLópez, M. (2005). Actinobacillus actinomycetemcomitans y Porphyromas ginngivalis en relación a las periodontitis agresivas. Revista Estomatológica Herediana, 15(2), 178 - 183.spa
dc.identifier.bibliographicCitationMaghsoodlou, M. T., Kazemipoor, N., Valizadeh, J., Seifi1, F. N., & Rahneshan, N. (2015). Essential oil composition of Eucalyptus microtheca and Eucalyptus viminalis. Avicenna journal of phytomedicine, 5(6), 540-552.spa
dc.identifier.bibliographicCitationMekonnen, A., Yitayew, B., Tesema, A., & Taddese, S. (2016). In Vitro Antimicrobial Activity of Essential Oil of Thymus schimperi, Matricariachamomilla, Eucalyptus globulus, and Rosmarinus officinalis. International Journal of Microbiology, 2016(1), 1-8.spa
dc.identifier.bibliographicCitationMinisterio de Salud y Protección Social. IV Estudio Nacional de Salud Bucal: ENSAB IV 2013-2014. Bogotá DC: Unión Temporal Sistemas Especializados de Información SEI S.A.spa
dc.identifier.bibliographicCitationMorales, A., Gandolfo, A., Bravo, J., Carvajal, P., Silva, N., Godoy, C., Garcia-Sesnich, J.,…Gamonal, J. (2018). Microbiological and clinical effects of probiotics and antibiotics on nonsurgical treatment of chronic periodontitis: a randomized placebo- controlled trial with 9-month follow-up. Journal of Applied Oral Science, 26(1), 1-9.spa
dc.identifier.bibliographicCitationMulyaningsih, S., Sporer, F., Reichling, J., & Wink, M. (2011). Antibacterial activity of essential oils from Eucalyptus and of selected components against multidrug-resistant bacterial pathogens. Pharmaceutical biology, 49(9), 893–899.spa
dc.identifier.bibliographicCitationOlolade, Z. S., & Olawore, N. O. (2017). Characterization of Essential Oil from the Seed of Eucalyptus cloeziana and Evaluation of its Modes of Medicinal Potentials. Edorium Journal of Infectious Diseases, 3(1), 1–8.spa
dc.identifier.bibliographicCitationOlsen, I., & Singhrao, S. K. (2018). Importance of heterogeneity in Porhyromonas gingivalis lipopolysaccharide lipid A in tissue specific inflammatory signalling. Journal of oral microbiology, 10(1440128), 1-10.spa
dc.identifier.bibliographicCitationOscarsson, J., Claesson, R., Lindholm, M., Höglund Åberg, C., & Johansson, A. (2019). Tools of Aggregatibacter actinomycetemcomitans to Evade the Host Response. Journal of clinical medicine, 8(7), 1079-1091.spa
dc.identifier.bibliographicCitationPardo, C. G., Monsalve, G. S., Erira, A., Espinosa, Y., y Jaramillo, G. I. (2017). Efecto antimicrobiano del aceite esencial de Citrus reticulata sobre Fusobacterium nucleatum asociada a enfermedad periodontal. Revista Colombiana de Biotecnología, 19(2), 7-14.spa
dc.identifier.bibliographicCitationPark, J., Shokeen, B., Haake, S. K., & Lux, R. (2016). Characterization of Fusobacterium nucleatum ATCC 23726 adhesins involved in strain-specific attachment to Porphyromonas gingivalis. International Journal of Oral Science, 8(3), 138–144.spa
dc.identifier.bibliographicCitationRagul, P., Dhanraj, M., & Ashish, R. J. (2018). Efficacy of eucalyptus oil over chlorhexidine mouthwash in dental practice. Drug Invention Today, 10(5), 638-641.spa
dc.identifier.bibliographicCitationRaja, M., Ummer, F., & Dhivakar, C. P. (2014). Aggregatibacter actinomycetemcomitans - a tooth killer?. Journal of clinical and diagnostic research: JCDR, 8(8), ZE13–ZE16.spa
dc.identifier.bibliographicCitationRamos, D., Moromi, H. y Martínez, E. (2011). Porphyromonas gingivalis: patógeno predominante en la periodontitis crónica. Revista Odontología Sanmarquina, 14(1), 34-38.spa
dc.identifier.bibliographicCitationSebei, K., Sakouhi, F., Herchi, W., Khouja, M. L., & Boukhchin, S. (2015). Chemical composition and antibacterial activities of seven Eucalyptus species essential oils leaves. Biological Research, 48(7), 1-7.spa
dc.identifier.bibliographicCitationShah, R., Donde, R., Mitra, D., Rodrigues, S., Shetty, G., Prithyani, S., & Vijayakar, H. (2018). Herbal periodontology- a review. International Journal For Research In Health Sciences And Nursing, 4(9), 1-10.spa
dc.identifier.bibliographicCitationSimsek, M., & Duman, R. (2017). Investigation of effect of 1,8-cineole on antimicrobial activity of chlorhexidine gluconate. Farmacognosy Research, 9(3), 234-237.spa
dc.identifier.bibliographicCitationSudhoff, H., Klenke, C., Greiner, J. F., Müller, J., Brotzmann, V., Ebmeyer, J., Kaltschmidt, B.,…Kaltschmidt, C. (2015). 1,8-Cineol Reduces Mucus-Production in a Novel Human Ex Vivo Model of Late Rhinosinusitis. Public Library of Science ONE, 10(7), 1-12.spa
dc.identifier.bibliographicCitationThurnheer, T., Karygianni, L., Flury, M., & Belibasakis, G. N. (2019). Fusobacterium Species and Subspecies Differentially Affect the Composition and Architecture of Supra- and Subgingival Biofilms Models. Frontiers Microbiology, 10(1716), 1-11.spa
dc.identifier.bibliographicCitationVega, B. A., Belinka, B. A., Jr, & Kachlany, S. C. (2019). Aggregatibacter actinomycetemcomitans Leukotoxin (LtxA; Leukothera®): Mechanisms of Action and Therapeutic Applications. Toxins, 11(9), 489-510.spa
dc.identifier.bibliographicCitationVelusamy, S. K., Sampathkumar, V., Ramasubbu, N., Paster, B. J. & Fine, D. H. (2019). Aggregatibacter actinomycetemcomitans colonization and persistence in a primate model. Proceedings of the National Academy of Sciences, 116(44), 22307-22313.spa
dc.identifier.bibliographicCitationVinod, K. S., Sunil, K. S., Sethi, P., Bandla, R. C., Singh, S., & Patel, D. (2018). A Novel Herbal Formulation versus Chlorhexidine Mouthwash in Efficacy against Oral Microflora. Journal of International Society of Preventive & Community Dentistry, 8(2), 184–190.spa
dc.identifier.bibliographicCitationWinska, K., Maczka, W., Łyczko, L., Grabarczyk, M., Czubaszek, A., &Szumny, A. (2019). Essential Oils as Antimicrobial Agents—Myth or Real Alternative?. Molecules, 24(11), 1-21.spa
dc.identifier.bibliographicCitationXie, H. (2015). Biogenesis and function of Porphyromonas gingivalis outer membrane vesicles. Future microbiology, 10(9), 1517–1527.spa
dc.identifier.bibliographicCitationYadav, H. K., Yadav, R. K., Chandra, A., & Thakkar, R. R. (2016). The effectiveness of eucalyptus oil, orange oil, and xylene in dissolving different endodontic sealers. Journal of conservative dentistry, 19(4), 332–337.spa
dc.identifier.bibliographicCitationYadav, N., & Chandra, H. (2017) Suppression of inflammatory and infection responses in lung macrophages by eucaliptus oil and its constituent 1,8-cineole: Role of pattern recognition receptors TREM-1 and NLRP3, the MAP kinase regulator MKP-1, and NFκB. Public Library of Science ONE, 12(11), 1-19.spa
dc.identifier.bibliographicCitationZerón, A., y Porras, D. (2016). Fusobacterium nucleatum ¿Un patógeno periodontal promotor de carcinogénesis colorrectal?. Revista ADM, 73(6), 280-285.spa
dc.identifier.instnameinstname:Universidad Antonio Nariñospa
dc.identifier.reponamereponame:Repositorio Institucional UANspa
dc.identifier.repourlrepourl:https://repositorio.uan.edu.co/spa
dc.identifier.urihttp://repositorio.uan.edu.co/handle/123456789/2938
dc.language.isospaspa
dc.publisherUniversidad Antonio Nariñospa
dc.publisher.campusCúcutaspa
dc.publisher.facultyFacultad de Odontologíaspa
dc.publisher.programOdontologíaspa
dc.rightsAcceso abierto
dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.rights.coarhttp://purl.org/coar/access_right/c_abf2spa
dc.rights.licenseAttribution-NoDerivatives 4.0 International (CC BY-ND 4.0)spa
dc.rights.urihttps://creativecommons.org/licenses/by-nd/4.0/spa
dc.subjectFusobacterium nucleatumes_ES
dc.subjectPorphyromonas gingivalises_ES
dc.subjectAggregatibacter actinomycetemcomitanses_ES
dc.subjectFitoterapiaes_ES
dc.subjectAceites esencialeses_ES
dc.subjectEucaliptoes_ES
dc.subject.keywordFusobacterium nucleatumes_ES
dc.subject.keywordPorphyromonas gingivalises_ES
dc.subject.keywordAggregatibacter actinomycetemcomitanses_ES
dc.subject.keywordHerbal medicinees_ES
dc.subject.keywordEssential oiles_ES
dc.subject.keywordEucalyptuses_ES
dc.titleEfecto antimicrobiano in vitro del aceite esencial eucalyptus globulus labill sobre fusobacterium nucleatum, porphyromonas gingivalis y aggregatibacter actinomycetemcomitans. Revisión de la literaturaes_ES
dc.typeTrabajo de grado (Pregrado y/o Especialización)spa
dc.type.coarhttp://purl.org/coar/resource_type/c_7a1fspa
dc.type.coarversionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.versioninfo:eu-repo/semantics/acceptedVersionspa
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