Determinación de la actividad antiviral in vitro de derivados de miricetina de Marcetia taxifolia contra los virus del chikungunya, zika y dengue.
dc.contributor.advisor | Losada Barragán, Mónica | spa |
dc.contributor.advisor | Upegui Zapata, Yulieth Alexandra | spa |
dc.contributor.author | Cuéllar Quimbaya, Andrés Felipe | spa |
dc.creator.cedula | 11821722519 | spa |
dc.date.accessioned | 2023-04-15T16:32:10Z | |
dc.date.available | 2023-04-15T16:32:10Z | |
dc.date.issued | 2022-11-18 | spa |
dc.description.abstract | Zika, dengue and chikungunya viruses are implicated in emerging and re emerging epidemics in tropical and subtropical countries such as Colombia, becoming a public health problem, with a negative impact on the quality of life of the population due to the morbidity and mortality associated with their sequelae. Today there is no specific antiviral treatment, only for dengue there is a vaccine whose efficacy is not clear. This makes the development of therapeutic agents essential. Plants are a key point in the search for new molecules with potential biological action since their compounds have medicinal properties. | |
dc.description.degreelevel | Pregrado | spa |
dc.description.degreename | Bioquímico(a) | spa |
dc.description.degreetype | Investigación | spa |
dc.description.notes | Presencial | spa |
dc.description.tableofcontents | Los virus zika, dengue y chikungunya están implicados en epidemias emergentes y reemergentes en países tropicales y subtropicales como Colombia, convirtiéndose en un problema de salud pública, con impacto negativo en la calidad de vida de la población debido a la morbimortalidad asociadas a sus secuelas. Hoy en día no existe un tratamiento antiviral específico, solo para dengue se cuenta con una vacuna de la cual no se tiene claridad en su eficacia. Lo que hace primordial el desarrollo de agentes terapéuticos. Las plantas son un punto clave en la búsqueda de nuevas moléculas con potencial acción biológica, ya que sus compuestos tienen propiedades medicinales. | |
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dc.identifier.bibliographicCitation | Álvarez-Díaz, D. A., Valencia-Álvarez, E., Rivera, J. A., Rengifo, A. C., Usme-Ciro, J. A., Peláez-Carvajal, D., Lozano-Jiménez, Y. Y., & Torres-Fernández, O. (2021a). An updated RT-qPCR assay for the simultaneous detection and quantification of chikungunya, dengue and zika viruses. Infection, Genetics and Evolution, 93. https://doi.org/10.1016/j.meegid.2021.104967 | spa |
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dc.identifier.bibliographicCitation | Buendia-Atencio, C., Pieffet, G. P., Montoya-Vargas, S., Martínez Bernal, J. A., Rangel, H. R., Muñoz, A. L., Losada-Barragán, M., Segura, N. A., Torres, O. A., Bello, F., Suárez, A. I., & Rodríguez, A. K. (2021). Inverse Molecular Docking Study of NS3-Helicase and NS5-RNA Polymerase of Zika Virus as Possible Therapeutic Targets of Ligands Derived from Marcetia taxifolia and Its Imp | spa |
dc.identifier.bibliographicCitation | Carabali, M., Jaramillo, G.-I., Rivera, V., Restrepo, B. N., Zinser, K., & gloria.jaramillor@campusucc.edu.co. (2019). Biomedica : revista del Instituto Nacional de Salud. In XVII Congreso Colombiano de Parasitología y Medicina Tropical. Universidad Cooperativa de Colombia, Facultad de Ciencias de la Salud, Medicina, Villavicencio. https://repository.ucc.edu.co/handle/20.500.12494/18362 | spa |
dc.identifier.instname | instname:Universidad Antonio Nariño | spa |
dc.identifier.reponame | reponame:Repositorio Institucional UAN | spa |
dc.identifier.repourl | repourl:https://repositorio.uan.edu.co/ | spa |
dc.identifier.uri | http://repositorio.uan.edu.co/handle/123456789/7967 | |
dc.language.iso | spa | spa |
dc.publisher | Universidad Antonio Nariño | spa |
dc.publisher.campus | Bogotá - Circunvalar | spa |
dc.publisher.faculty | Facultad de Ciencias | spa |
dc.publisher.program | Bioquímica | spa |
dc.rights | Acceso abierto | |
dc.rights.accessrights | info:eu-repo/semantics/openAccess | spa |
dc.rights.coar | http://purl.org/coar/access_right/c_abf2 | spa |
dc.rights.license | Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) | spa |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/ | spa |
dc.subject | Arbovirus | es_ES |
dc.subject | Zika | es_ES |
dc.subject | Dengue | es_ES |
dc.subject | Chikungunya | es_ES |
dc.subject | Antiviral | es_ES |
dc.subject.ddc | T 40.23 C967d | es_ES |
dc.subject.keyword | Arbovirus | es_ES |
dc.subject.keyword | Zika | es_ES |
dc.subject.keyword | Dengue | es_ES |
dc.subject.keyword | Chikungunya | es_ES |
dc.subject.keyword | Antiviral | es_ES |
dc.title | Determinación de la actividad antiviral in vitro de derivados de miricetina de Marcetia taxifolia contra los virus del chikungunya, zika y dengue. | es_ES |
dc.type | Trabajo de grado (Pregrado y/o Especialización) | spa |
dc.type.coar | http://purl.org/coar/resource_type/c_7a1f | spa |
dc.type.coarversion | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |
dc.type.version | info:eu-repo/semantics/acceptedVersion | spa |
dcterms.audience | Especializada | spa |
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