Efecto cicatrizante y antiinflamatorio del aloe vera y la vitamina c en mucosa oral. Revisión narrativa de la literatura

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dc.contributor.advisorDíaz Mora, Norma Patriciaspa
dc.contributor.advisorRamírez Sulvarán, Jesús Arturospa
dc.contributor.authorDávila Cuellar, Angélica Maríaspa
dc.contributor.authorGalavis Villamizar, Yulian Andreaspa
dc.creator.cedula1034304856spa
dc.creator.cedula1094533717spa
dc.date.accessioned2021-03-09T22:10:26Z
dc.date.available2021-03-09T22:10:26Z
dc.date.issued2020-11-25spa
dc.descriptionPropiaes_ES
dc.description.abstractObjective: The objective of this narrative review of the literature was to determine the healing and anti-inflammatory effect of Aloe vera and vitamin C on oral mucosa. Materials and methods: 126 articles related to the objective of the study were collected, these articles were read and analyzed and 50 of them were selected according to the inclusion and exclusion criteria, where the search parameter was the words: “Aloe” “inflammation” “mucosa” “cicatrization” “bacteria” “Ascorbic Acid” “wound healing” and Boolean operators such as “AND and “OR” were used applying the search to a period of the last 20 years. Results: When analyzing the results, it was determined that Aloe vera had a healing and anti-inflammatory effect in various lesions of the oral mucosa since it acts in the arachidonic acid pathway through cyclooxygenase, inhibiting inflammation, and it also did not present side effects in the clinical studies carried out. In patients, with respect to vitamin C it was determined that it has a healing and anti-inflammatory effect on oral mucosa since it regulates the inflammatory process and stimulates tissue repair, in addition, it modulates the release of catabolic inflammatory cytokines, promotes wound healing, Aloe vera had a high antibacterial effect against a variety of oral pathogens. Conclusion: Aloe vera and vitamin C are effective alternative treatments in terms of the healing and anti-inflammatory effect on oral mucosa lesions, however, regarding vitamin C there are no clinical studies regarding its direct topical application on oral mucosa and there is a controversy regarding its dosage. Aloe vera has an antibacterial effect against pathogens of the oral cavity, however, clinical studies are needed to determine what other pathogens Aloe vera can inhibit. Keywords: Aloe, ascorbic acid, mucosa, wound healing, inflammation, bacteria.eng
dc.description.abstractObjetivo: el objetivo de esta revisión narrativa de la literatura fue determinar el efecto cicatrizante y antiinflamatorio del Aloe vera y la vitamina C en mucosa oral. Materiales y métodos: Se recopilaron 126 artículos relacionados con el objetivo del estudio, se realizó la lectura y el análisis de estos artículos y se seleccionaron 50 de estos según los criterios de inclusión y exclusión, donde se tuvo como parámetro de búsqueda las palabras: “Aloe” “inflammation” “mucosa” “cicatrización” “bacterias” Ascorbic Acid” “wound healing” y se utilizaron operadores booleanos como “AND y “OR” aplicando la búsqueda a un periodo de los últimos 20 años. Resultados: Al analizar los resultados se determinó que el Aloe vera presentó efecto cicatrizante y antiinflamatorio en diversas lesiones de la mucosa oral ya que actúa en la vía del ácido araquidónico a través de la ciclooxigenasa inhibiendo la inflamación, además no presentó efectos secundarios en los estudios clínicos realizados a pacientes, con respecto a la vitamina C se determinó tiene efecto cicatrizante y antiinflamatorio en mucosa oral ya que regula el proceso inflamatorio y estimula la reparación de los tejidos, además, modula la liberación de citocinas inflamatorias catabólicas, promueve la cicatrización de la herida, El Aloe vera presentó alto efecto antibacterial contra una variedad de patógenos orales. Conclusión: El Aloe vera y la vitamina C son tratamientos alternativos efectivos en cuanto al efecto cicatrizante y antiinflamatorio en lesiones de la mucosa oral, sin embargo, en cuanto a la vitamina C no hay estudios clínicos respecto a su aplicación tópica directa en mucosa oral y hay una controversia en cuanto a su dosificación. El Aloe vera tiene efecto antibacterial contra patógenos propios de la cavidad oral, sin embargo, hacen falta estudios clínicos para determinar que otros patógenos puede inhibir el Aloe vera. Palabras clave: Aloe, ácido ascórbico, mucosa bucal, cicatrización, inflamación, bacterias.spa
dc.description.degreelevelPregradospa
dc.description.degreenameOdontólogo(a)spa
dc.description.notesPresencialspa
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dc.identifier.bibliographicCitationXue, M., & Jackson, C. J. (2015). Extracellular Matrix Reorganization During Wound Healing and Its Impact on Abnormal Scarring. Advances in wound care, 4(3), 119–136.spa
dc.identifier.bibliographicCitationYeomans, N. (2015). Consensus about managing gastrointestinal and cardiovascular risks of nonsteroidal anti-inflammatory drugs. BMC Medicine, 13(1).spa
dc.identifier.bibliographicCitationYeturu, S. K., Acharya, S., Urala, A. S., & Pentapati, K. C. (2016). Effect of Aloe vera, chlorine dioxide, and chlorhexidine mouth rinses on plaque and gingivitis: A randomized controlled trial. Journal of Oral Biology and Craniofacial Research, 6(1), 55-59.spa
dc.identifier.bibliographicCitationYussif, N. M., Abdul Aziz, M. A., & Abdel Rahman, A. R. (2016). Evaluation of the Anti-Inflammatory Effect of Locally Delivered Vitamin C in the Treatment of Persistent Gingival Inflammation: Clinical and Histopathological Study. Journal of nutrition and metabolism, 2978741.spa
dc.identifier.bibliographicCitationYussif, N. M., Dehis, M. H., & Rahman, A. R. (2018). Efficacy and safety of locally injectable vitamin C on accelerating the orthodontic movement of maxillary canine impaction (oral mesotherapy technique): prospective study. Clinical Cases in Mineral and Bone Metabolism, 5(2), 280-287.spa
dc.identifier.instnameinstname:Universidad Antonio Nariñospa
dc.identifier.reponamereponame:Repositorio Institucional UANspa
dc.identifier.repourlrepourl:https://repositorio.uan.edu.co/spa
dc.identifier.urihttp://repositorio.uan.edu.co/handle/123456789/2947
dc.language.isospaspa
dc.publisherUniversidad Antonio Nariñospa
dc.publisher.campusCúcutaspa
dc.publisher.facultyFacultad de Odontologíaspa
dc.publisher.programOdontologíaspa
dc.rightsAcceso abierto
dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.rights.coarhttp://purl.org/coar/access_right/c_abf2spa
dc.rights.licenseAttribution-NoDerivatives 4.0 International (CC BY-ND 4.0)spa
dc.rights.urihttps://creativecommons.org/licenses/by-nd/4.0/spa
dc.subjectAloees_ES
dc.subjectÁcido ascórbicoes_ES
dc.subjectMucosa bucales_ES
dc.subjectCicatrizaciónes_ES
dc.subjectInflamaciónes_ES
dc.subjectBacteriases_ES
dc.subject.keywordAloees_ES
dc.subject.keywordAscorbic acides_ES
dc.subject.keywordMucosaes_ES
dc.subject.keywordWound healinges_ES
dc.subject.keywordInflammationes_ES
dc.subject.keywordBacteriaes_ES
dc.titleEfecto cicatrizante y antiinflamatorio del aloe vera y la vitamina c en mucosa oral. Revisión narrativa de la literaturaes_ES
dc.typeTrabajo de grado (Pregrado y/o Especialización)spa
dc.type.coarhttp://purl.org/coar/resource_type/c_7a1fspa
dc.type.coarversionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.versioninfo:eu-repo/semantics/acceptedVersionspa
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