Péptidos derivados de toxinas animales como moduladores de la actividad del receptor NMDA

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dc.audienceEspecializada
dc.contributor.advisorReyes Guzman, Edwin Alfredo
dc.contributor.advisorForero Vivas , Maria Elisa
dc.contributor.advisorForero Vivas, Maria Elisa
dc.contributor.authorAguilar Niño, Johann Sebastian
dc.date.accessioned2024-10-07T21:22:28Z
dc.date.available2024-10-07T21:22:28Z
dc.date.created0024-06-11
dc.date.issued2024-10-04
dc.descriptionPropia
dc.description.abstractThe NMDA receptor is involved in various physiological processes such as memory, synaptic plasticity, and signal transmission. It has been proven that dysfunction, inhibition, or overactivation of the NMDA receptor leads to various pathologies including Alzheimer's, cerebral ischemias, depression, and schizophrenia, among others. Experimental and clinical research suggests that peptides found in the venom of certain animals can modulate NMDA receptor activity and could be effective in treating these diseases. In this work, we conducted an exhaustive literature review on peptides that have been demonstrated through electrophysiology to modulate receptor activity
dc.description.degreelevelPregrado
dc.description.degreenameBioquímico(a)
dc.description.degreetypeMonografía
dc.description.notesPresencial
dc.description.sponsorshipUAN Proyectos de ciencia, tecnología, innovación y creación artística
dc.description.tableofcontentsEl receptor NMDA está involucrado en diversos procesos fisiológicos como memoria, plasticidad sináptica y transmisión de señales. Se ha comprobado que la disfunción, inhibición o sobreactivación del NMDA genera diversas patologías en donde se pueden encontrar alzheimer, isquemias cerebrales, depresión, esquizofrenia entre otras. Investigaciones experimentales y clínicas sugieren que en el veneno de algunos animales se encuentran péptidos que modulan la actividad del receptor NMDA y podrían ser efectivas para tratar estas enfermedades. En este trabajo se realizó la búsqueda exhaustiva de la literatura sobre péptidos demostrados mediante electrofisiología como moduladores de la actividad del receptor
dc.description.versionfinal
dc.identifier.urihttps://repositorio.uan.edu.co/handle/123456789/10295
dc.language.isoEspañol
dc.publisher.campusBogotá - Circunvalar
dc.publisher.facultyFacultad de Ciencias
dc.publisher.programBioquímica
dc.rightsAcceso restringido
dc.rights.accessrightsinfo:eu-repo/semantics/restrictedAccessspa
dc.rights.coarhttp://purl.org/coar/access_right/c_16ecspa
dc.rights.licenseAttribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)spa
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/spa
dc.sourcereponame:Repositorio Institucional UAN
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dc.subjectRecepctores NMDA
dc.subjectPeptidos
dc.subjectElectrofisiología
dc.subjectAntagonistas
dc.subjectAgonistas
dc.subject.keywordNMDA receptor
dc.subject.keywordPeptides
dc.subject.keywordElectrophysiology
dc.subject.keywordAntagonists
dc.subject.keywordAgonists
dc.titlePéptidos derivados de toxinas animales como moduladores de la actividad del receptor NMDA
dc.type.coarhttp://purl.org/coar/resource_type/c_7a1fspa
dc.type.coarversionhttp://purl.org/coar/version/c_b1a7d7d4d402bcce
dc.type.documentEstudio exploratorio
dc.type.localTesis/Trabajo de grado - Monografía - Pregradospa
dc.type.redcolhttp://purl.org/redcol/resource_type/PID
dc.type.versionVersión original del autor, Borrador, Manuscrito
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