Desarrollo de un bioinstrumento para estimar la impedancia acústica de la córnea utilizando método de inmersión biométrica a-scan

Abstract

The present academic proposal presents the development of an ultrasonic bioinstrument, which makes it possible to measure acoustic impedance in order to be able to correlate it with that with reference acoustic impedance, integrated in a biomedical instrument., not invasive - non-harmful, which incorporates ophthalmological advantages in clinical diagnosis, such as: the minimization of instruments in direct contact with structures of the patient's eye to reduce the risk of trauma, injury and infection and consequently avoid the use of anesthetic agents. The system to be implemented includes the design, integration, development and interrelationship of hardware: a) high frequency ultrasonic transducers; b) an integrated system of electric pulse generator and digital signal acquisition; c) a microcontroller for the activation of A-scan inspection and, d) the manufacture of mechanical devices ("Modification of a praguer cup") as an acoustic coupling system and integration of the electronic instrumentation for the acquisition of signals to be transmitted to the computer. And software that includes the development of computational characterization algorithms quantitative ultrasonics that will be developed in Matlab. Ultrasonic insonification, initially is validated on the manufacture of ocular acoustic Phantoms and later on bio-models. The validation of the bioinstrument should include an experimental test in patients with respective informed consent and comparing the results with values from the literature. The expected results were obtained from the bioinstrument, since the acoustic impedance values presented are very close to the literature with an average error percentage of 6.10% for patients with open eyes and 17.81% with closed eyes. Thus concluding that the bioinstrument contributes to the measurement of acoustic parameters in the human eye.