Diseño y evaluación de algoritmos de análisis de desempeño y control para sistemas de administración automática de insulina en pacientes con diabetes

Abstract

This book represents the result of four years of dedicated research. It presents various algorithms related to the performance analysis and control of automated insulin delivery systems in patients with diabetes. These algorithms include: (1) a glucose controller for automated insulin delivery systems, (2) a safety strategy to prevent hypoglycemic events in insulin therapy, and (3) an analytical approach for analysis of glycemic variability in preclinical and clinical diabetes trials.