Evaluación del efecto de la dieta cetogénica y los ácidos grasos octanoico y decanoico sobre los genes modulados por PPARs en el desarrollo de tumores de glioblastoma: estudio de investigación con modelo in vitro de la línea celular T98G e in vivo de pez cebra.

Abstract

Glioblastoma is an aggressive and difficult to treat type of brain tumor. However, it has been proposed that ketogenic therapy could have beneficial effects in controlling its tumor activity. This diet, rich in fatty acids, acts as natural ligands for PPAR receptors, which regulate inflammatory, metabolic and cell growth processes.