Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)Gutiérrez Ramírez, David A.Ospina Muñoz, CarolinaMurillo Peña, EdwinMolina Higuera, GeraldineGarcía Vélez, Yesica2024-03-052024-03-052023-12-02http://repositorio.uan.edu.co/handle/123456789/9561Introduction. The application of LLLT low power laser is a therapy that has been used in different health applications, including in dentistry to reduce inflammation, pain control, tissue regeneration stimulation, among others. Although in orthodontics it is used during treatment with fixed appliances to accelerate the bone remodeling process, the underlying molecular bases that govern this process are unknown.Introducción. La aplicación de láser de baja potencia LLLT es una terapia que se viene empleando en diferentes aplicaciones en salud, incluido en odontología para la disminución de la inflamación, control del dolor, estimulación de regeneración de tejidos, entre otras. Aunque en ortodoncia se utiliza durante el tratamiento con aparatología fija para acelerar el proceso de remodelado óseo, se desconocen las bases moleculares subyacentes que gobiernan este proceso. Objetivo. Establecer la función de los genes que se expresan en las células madre de la papila dental osteoinducidas estimuladas con láser de baja potencia.spaAcceso abiertotranscriptómicacélulas madreláser de baja potenciaTrabajo de grado (Pregrado y/o Especialización)transcriptomicsstem cellslow power laserinfo:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf21. Fleming P. Timing orthodontic treatment: early or late? Australian dental journal. 2017;62 Suppl 1.2. Nimeri G, Kau C, Abou-Kheir N, Corona R. Acceleration of tooth movement during orthodontic treatment--a frontier in orthodontics. Progress in orthodontics. 2013;14.3. Carroll JD, Milward MR, Cooper PR, Hadis M, Palin WM. Developments in low level light therapy (LLLT) for dentistry. Dent Mater. 2014;30(5):465-75.4. Lins RD, Dantas EM, Lucena KC, Catao MH, Granville-Garcia AF, Carvalho Neto LG. Biostimulation effects of low-power laser in the repair process. An Bras Dermatol. 2010;85(6):849-55.5. Soleimani M, Abbasnia E, Fathi M, Sahraei H, Fathi Y, Kaka G. The effects of low-level laser irradiation on differentiation and proliferation of human bone marrow mesenchymal stem cells into neurons and osteoblasts--an in vitro study. Lasers Med Sci. 2012;27(2):423-30.6. Makhlouf M, Dahaba MM, Tuner J, Eissa SA, Harhash TA. Effect of adjunctive low level laser therapy (LLLT) on nonsurgical treatment of chronic periodontitis. Photomed Laser Surg. 2012;30(3):160-6.7. Acosta M, Guerrero D, La Mantia P, Lunini P, Uzcátegui R. Use of low level laser in dentistry: Orthodontics and periodontics. 2. 2014;2:170:85.8. Farivar S, Malekshahab iT, Shiari R. Biological Effects of Low Level Laser Therapy. Journal of lasers in medical sciences. 2014;5(2).9. Baloul S. Osteoclastogenesis and Osteogenesis during Tooth Movement. Frontiers of oral biology. 2016;18.10. Huang H, Williams R, Kyrkanides S. Accelerated orthodontic tooth movement: molecular mechanisms. American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics. 2014;146(5).instname:Universidad Antonio Nariñoreponame:Repositorio Institucional UANrepourl:https://repositorio.uan.edu.co/