Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)Alfonso Rodríguez, Camilo AndrésGarzón Vergara, Hernán SantiagoAristizábal Marulanda, Isabel CristinaChila Bosso, Angela VivianaCorrea Aponte, Nicolás2022-07-052022-07-052022-05-19http://repositorio.uan.edu.co/handle/123456789/6676This research work focuses on the in vitro analysis of the relationship between biomaterials and components of natural origin, as a possible adjuvant treatment for periodontitis. It is known that the chronic inflammation of the gingival tissue is caused by an immune hyperresponse caused by the accumulation of dental biofilm on the root surface, triggering the progressive destruction of the periodontal tissues, compromising the support and stability of the teeth. Over time, different treatment alternatives have been proposed as adjuvants to scaling and root planing, such as: antibiotics, analgesics, probiotics, alternative therapies, among others.El presente trabajo de investigación se centra en el análisis in vitro de la relación de biomateriales y componentes de origen natural, como posible tratamiento coadyuvante para la periodontitis. Se conoce que la inflamación crónica del tejido gingival está dada por una hiperrespuesta inmunitaria causada por el acúmulo de biofilm dental en la superficie radicular, desencadenando la destrucción progresiva de los tejidos periodontales comprometiendo el soporte y la estabilidad de los dientes. A través del tiempo, se han propuesto diferentes alternativas de tratamiento como coadyuvantes al raspaje y alisado radicular, como: antibióticos, analgésicos, probióticos, terapias alternativas, entre otrosspaAcceso a solo metadatosIngeniería TisularRegeneración PeriodontalMembranas de ColágenoPeriodoncia617.6Trabajo de grado (Pregrado y/o Especialización)Tissue engineeringPeriodontal regenerationCollagen membranesPeriodonciainfo:eu-repo/semantics/closedAccesshttp://purl.org/coar/access_right/c_14cbNazir M. A. (2017). Prevalence of periodontal disease, its association with systemic diseases and prevention. International journal of health sciences, 11(2), 72–80.Hajishengallis G. (2015). Periodontitis: from microbial immune subversion to systemic inflammation. Nature reviews. Immunology, 15(1), 30–44.s. https://doi.org/10.1038/nri3785.Acquier, A. B., De Couto Pita, A. K., Busch, L., & Sánchez, G. A. (2017). Parameters of oxidative stress in saliva from patients with aggressive and chronic periodontitis. Redox report: communications in free radical research, 22(3), 119–126. https://doi.org/10.1080/13510002.2016.1198104Liao, Y., Li, H., Shu, R., Chen, H., Zhao, L., Song, Z., & Zhou, W. (2020). Mesoporous Hydroxyapatite/Chitosan Loaded with Recombinant-Human Amelogenin Could Enhance Antibacterial Effect and Promote Periodontal Regeneration. Frontiers in cellular and infection microbiology, 10, 180. https://doi.org/10.3389/fcimb.2020.00180Caton, J. G., Armitage, G., Berglundh, T., Chapple, I., Jepsen, S., Kornman, K. S., Mealey, B. L., Papapanou, P. N., Sanz, M., & Tonetti, M. S. (2018). A new classification scheme for periodontal and peri-implant diseases and conditions - Introduction and key changes from the 1999 classification. Journal of clinical periodontology, 45 Suppl 20, S1–S8. https://doi.org/10.1111/jcpe.12935Bunte, K., Hensel, A., & Beikler, T. (2019). Polyphenols in the prevention and treatment of periodontal disease: A systematic review of in vivo, ex vivo and in vitro studies. Fitoterapia, 132, 30–39. https://doi.org/10.1016/j.fitote.2018.11.012Gleiznys, D., Gleiznys, A., Abraškevičiūtė, L., Vitkauskienė, A., Šaferis, V., & Sakalauskienė, J. (2019). Interleukin-10 and Interleukin-1β Cytokines Expression in Leukocytes of Patients with Chronic Peri-Mucositis. Medical science monitor : international medical journal of experimental and clinical research, 25, 7471–7479. https://doi.org/10.12659/MSM.915464.Ortolani, E., Quadrini, F., Bellisario, D., Santo, L., Polimeni, A., & Santarsiero, A. (2015). Mechanical qualification of collagen membranes used in dentistry. Annali dell'Istituto superiore di sanita, 51(3), 229–235. https://doi.org/10.4415/ANN_15_03_11Bunyaratavej, P., & Wang, H. L. (2001). Collagen membranes: a review. Journal of periodontology, 72(2), 215–229. https://doi.org/10.1902/jop.2001.72.2.215Kornman K. S. (2018). Contemporary approaches for identifying individual risk for periodontitis. Periodontology 2000, 78(1), 12–29. https://doi.org/10.1111/prd.12234instname:Universidad Antonio Nariñoreponame:Repositorio Institucional UANrepourl:https://repositorio.uan.edu.co/